Yes, you can use TotalBoat TotalStrip to remove acrylic paint. Apply TotalBoat TotalStrip between 1/4 to 1/2 inch thick using a brush, putty knife, or roller, and give it time to work through the layers of paint. Use a stiff brush or putty knife to remove the paint. Use water and a brush or stripping pade to remove any remaining residue. Allow the surface to dry completely.