Yes, you can apply TotalBoat Wet Edge marine topside paint directly to a surface coated with TotalBoat Gleam 2.0 varnish that has cured for at least 48 hours under proper curing conditions. Before applying Wet Edge, sand the cured Gleam 2.0 surface lightly, until smooth, with 220-grit or 320-grit sandpaper. Remove all sanding residue, as directed, and allow the surface to dry completely.